Alternate Names | GP3A,GPIIIa,ITGB3,Integrin beta-3 |
Uniprot ID | P05106 |
Background | CD61, also known as integrin 3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin +V (CD51) to form±V/3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins. |
Form | Liquid |
Clone No. | VI-PL2 (See Other Available Formats) |
Host | Mouse |
Isotype | Mouse IgG1, |
Isotype Control | Mouse IgG1, Isotype Control(APC Conjugated)[MOPC-21] [Product E-AB-F09792E] |
Reactivity | Human |
Application | FCM (See the Application Description) |
Storage Buffer | PBS with 0.05% Proclin300, 1% BSA |
Shipping | Biological ice pack at 4 |
Stability & Storage | Keep as concentrated solution. Store at 2~8 and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
SR GROUP
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