Alternate Names | T-lymphocyte activation antigen CD86,Cd86,Activation B7-2 antigen,Early T-cell costimulatory molecule 1,ETC-1 |
Uniprot ID | P42081 |
Background | CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
Form | Liquid |
Clone No. | BU63 (See Other Available Formats) |
Host | Mouse |
Isotype | Mouse IgG1, |
Isotype Control | Mouse IgG1, Isotype Control(PE/Cyanine5 Conjugated)[MOPC-21] [Product E-AB-F09792G] |
Reactivity | Human |
Application | FCM (See the Application Description) |
Storage Buffer | PBS with 0.05% Proclin300, 1% BSA |
Shipping | Biological ice pack at 4 |
Stability & Storage | Keep as concentrated solution. Store at 2~8 and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
SR GROUP
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