Plasmocin is a broad-spectrum mycoplasma and related cell wall-less bacteria removal reagent. It is effective against all common mycoplasma strains, both extracellular and intracellular.
For maximum efficiency, Plasmocin contains a formulation of two antibiotics: the first one blocks protein synthesis, and the second one stops DNA replication. Another component, which is actively transported into mammalian cells, ensures that following treatment, cell cultures do not become re-infected. Thus, Plasmocin is more effective than other reagents on the market in eradicating mycoplasma and preventing resistant strain generation [1]. Many cell lines infected by mycoplasmas have been successfully treated with Plasmocin[2], including primary cancer cell lines [3], virus-producing cells [4], and induced pluripotent stem cells [5], without inducing any permanent alterations.
This mycoplasma removal reagent is available in two formats:
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