Product Description
DESCRIPTION
Capsaicin is the primary active component of the heat and pain-eliciting lipid-soluble fraction of the Capsicum pepper.1 Capsaicin is present in natural hot pepper extracts along with a number of impurities, including dihydrocapsaicin and several lesser impurities. Separation by HPLC is required in order to obtain capsaicin of consistently high purity and reproducible quality.2Â VR1 is a heat-activated calcium ion channel which functions as part of the normal nociceptive pain pathway. Capsaicin elicits a sensation of burning pain by activation of VR1 on small, non-myelinated polymodal C-type nociceptive nerve fibers.3Â Chronic application of capsaicin leads to desensitization of these pain fibers and has been widely exploited in various non-prescription pain remedies. TECHNICAL INFORMATION
Formal Name
N-[(4-hydroxy-3-methoxyphenyl)methyl]-6E-8-methyl-nonenamide
CAS Number
404-86-4
Molecular Formula
C18H27NO3
Formula Weight
305.4
Purity
95%
Formulation
A crystalline solid
max
230, 281 nm
SHIPPING & STORAGE
Storage
-20oC
Shipping
Room temperature in continental US; may vary elsewhere
Stability
2 years.