Product Description
Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper.1 Capsaicin is found in natural hot pepper extracts along with a number of impurities, including dihydrocapsaicin and several lesser impurities. Separation by HPLC is required in order to obtain pure dihydrocapsaicin.2 Dihydrocapsaicin represents about 10% of the compound present in commercial preparations purporting to be pure capsaicin. VR1 (vanilloid receptor 1) is a heat activated calcium ion channel which functions as a part of the normal nociceptive pain pathway. Capsaicin elicits a sensation of burning pain by activation of VR1 on small, non-myelinated polymodal C-type nociceptive nerve fibers.3 The potency of dihydrocapsaicin at VR1 appears equivalent to capsaicin.
N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-nonanamide
CAS Number
19408-84-5
Molecular Formula
C18H29NO3
Formula Weight
307.4
Purity
98%
Formulation
A crystalline solid
max
230, 281 nm
SHIPPING & STORAGE
-20oC
Shipping
Room temperature in continental US; may vary elsewhere
Stability
2 years